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Referral and warning signs
When to refer
Urgent Referral to Hospital: Complicated SAM. Any malnourished child with a General Danger Sign or severe classification. Child with MAM who deteriorates or fails to improve despite counseling/support. Uncomplicated SAM <6 months old (needs specialized feeding support).
Red flags
- Bilateral pitting oedema.
- MUAC < 115 mm.
- WFH/L < -3 Z-scores.
- Any General Danger Sign in a malnourished child.
- Failed appetite test.
- Medical complications (severe dehydration, shock, severe anaemia, high fever, hypothermia).
Signs and symptoms
- Ask (Feeding Assessment):
- - If <= 6m: Breastfeeding pattern (frequency, exclusivity)?
- - If >= 6m: Appetite (able to finish portion)? Usual feeding habits (what foods, frequency, separate serving)?
- - Food availability at home?
- - Compare current feeding with age-appropriate recommendations (See PED020).
- Look and Feel (Nutritional Status Assessment):
- - Look for visible severe wasting.
- - Look for oedema of BOTH feet.
- - Measure Weight-for-Height/Length (WFH/L) Z-score (preferred).
- - OR Measure Weight-for-Age (WFA) Z-score.
- - Measure Mid-Upper Arm Circumference (MUAC) in children >= 6 months.
- If Severe Acute Malnutrition (SAM) identified (Oedema OR WFH/L <-3z OR MUAC <115mm):
- - Check for medical complications (Any general danger sign? Any severe classification? Pneumonia with chest indrawing?).
- - Perform Appetite Test (Offer Ready-to-Use Therapeutic Food - RUTF) if child >=6 months and no medical complications.
- - Assess breastfeeding if child <6 months.
Risk factors
- Inadequate food intake (quantity or quality).
- Frequent infections (diarrhoea, pneumonia, measles, HIV, TB).
- Poor feeding practices (inappropriate complementary feeding, infrequent feeding).
- Poverty / Food insecurity.
- Poor sanitation and hygiene.
Diagnosis
Clinical assessment
Assessment based on presence of bilateral pitting oedema, measurement of WFH/L Z-score, MUAC, or WFA Z-score, combined with feeding assessment and check for medical complications.
Investigations
- Anthropometric measurements (Weight, Height/Length, MUAC).
- Plotting on WHO Growth Standards charts.
- Appetite test (using RUTF) for SAM classification.
- Assessment of feeding practices.
- Check for medical complications (as per IMCI assessment).
Diagnostic criteria
IMCI Classification based on findings: - Complicated Severe Acute Malnutrition (SAM): Oedema OR WFH/L <-3z OR MUAC <115mm AND (Any Medical Complication OR Failed Appetite Test OR Breastfeeding Problem <6m). - Uncomplicated Severe Acute Malnutrition (SAM): WFH/L <-3z OR MUAC <115mm OR Very Low WFA AND No Medical Complications AND Passed Appetite Test (if >=6m). - Moderate Acute Malnutrition (MAM): WFH/L between -3z and -2z OR MUAC 115mm up to <125mm OR Low WFA. - No Acute Malnutrition: WFH/L >= -2z AND MUAC >= 125mm.
Management
Non-pharmacological management
- Complicated SAM:
- - Prevent low blood sugar (breastfeed/EBM/sugar water).
- - Keep child warm.
- - Refer URGENTLY to Hospital for inpatient therapeutic care (stabilization phase).
- Uncomplicated SAM (>=6m):
- - Outpatient Therapeutic Care (OTC) program.
- - Provide weekly supply of RUTF (Ready-to-Use Therapeutic Food) based on weight.
- - Counsel mother on RUTF use, hygiene, continued feeding, danger signs.
- - Assess for possible TB.
- - Follow up weekly initially, then bi-weekly.
- Uncomplicated SAM (<6m): Focus on optimizing exclusive breastfeeding. Refer to specialized support (lactation consultant/nutritionist).
- Moderate Acute Malnutrition (MAM):
- - Assess feeding and provide intensive counseling based on age-appropriate recommendations (See PED020).
- - If feeding problem identified, follow up in 7 days.
- - Provide supplementary feeding if available through programs (e.g., Corn Soya Blend - CSB).
- - Assess for possible TB.
- - Follow up monthly for reassessment and counseling.
- No Acute Malnutrition:
- - If child <2 years or feeding concerns: Assess feeding and counsel on age-appropriate recommendations.
- - If feeding problem identified, follow up in 7 days.
- - Promote continued good feeding practices.
Pharmacological treatment
- Complicated SAM:
- - Give FIRST DOSE pre-referral antibiotic (Ampicillin 50mg/kg IM + Gentamicin 7.5mg/kg IM OR Benzylpenicillin 50,000 IU/kg IM).
- - Hospital management includes therapeutic milk (F-75, F-100), electrolytes, micronutrients, antibiotics.
- Uncomplicated SAM:
- - Give routine Amoxicillin DT 40 mg/kg PO BID for 5 days at initiation of OTC.
- - RUTF contains necessary micronutrients; DO NOT give separate iron initially.
- - Routine deworming (Albendazole/Mebendazole if >1 year).
- - Measles vaccine if due.
- MAM: Routine deworming, Vitamin A if due.
- All Malnutrition: Assess immunization status and vaccinate as needed.
Monitoring
Weekly follow-up initially for Uncomplicated SAM (weight, MUAC, appetite, complications). Monthly follow-up for MAM. Monitor feeding practices and provide ongoing counseling.
Complications
- Increased susceptibility to and severity of infections.
- Hypothermia.
- Hypoglycaemia.
- Electrolyte imbalance.
- Heart failure (during refeeding).
- Impaired growth and development (stunting, cognitive deficits).
- Death.
Prevention
- Exclusive breastfeeding for 6 months.
- Appropriate complementary feeding from 6 months.
- Good hygiene and sanitation.
- Immunization.
- Micronutrient supplementation (Vitamin A).
- Deworming.
- Early detection and management of infections.
- Food security and poverty reduction.
Patient education
- Explanation of the child's nutritional status.
- Specific feeding recommendations based on age and status (breastfeeding, complementary foods, RUTF, supplementary foods).
- How to prepare/administer RUTF or supplementary foods.
- Importance of hygiene during food preparation and feeding.
- Need for routine medications (antibiotics, deworming).
- Danger signs requiring immediate return.
- Importance of follow-up appointments for monitoring progress.
Uganda-specific notes
High burden of malnutrition (both acute and chronic/stunting). MUAC is widely used for screening at community (VHT) and facility level. RUTF is standard for Uncomplicated SAM treatment in OTC programs. Need to integrate nutrition assessment/counseling into all child health contacts. Linkage with community nutrition programs important.
References
- Uganda Clinical Guidelines (UCG) 2023
Chapter 17, Section 17.3.6
- Uganda Clinical Guidelines (UCG) 2023
Chapter 19, Section 19.2 (Management of Malnutrition)
- IMCI Chart Booklet, MOH Uganda
(Malnutrition Algorithm)
- Integrated Management of Acute Malnutrition Guidelines, MOH Uganda
(Detailed protocols for SAM/MAM)