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Respiratory System

Coryza (Common Cold)

Acute, self-limiting viral inflammation of the upper respiratory tract, primarily affecting the nasal mucosa (rhinitis) and pharynx (rhinopharyngitis).

Also known as: Common Cold, Rhinitis, Rhinopharyngitis, URTI

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Referral and warning signs

When to refer

Referral usually not necessary. Seek medical advice if: High fever (>38.5°C) or prolonged fever. Severe symptoms. Difficulty breathing / Shortness of breath. Chest pain. Symptoms worsen or fail to improve after 10-14 days. Suspected complications (ear pain, severe headache/facial pain, productive cough with fever). Underlying chronic illness.

Red flags

  • High fever
  • Difficulty breathing / Respiratory distress
  • Severe sore throat or difficulty swallowing
  • Severe headache or stiff neck
  • Symptoms persisting >14 days or worsening

Signs and symptoms

  • Sudden onset.
  • Nasal congestion / blockage.
  • Rhinorrhea (runny nose) - initially clear, may become thicker/colored.
  • Sneezing.
  • Sore throat or scratchy throat.
  • Mild cough (usually dry).
  • Malaise, mild fatigue.
  • Headache (mild).
  • Low-grade fever may occur, especially in children.
  • Watery eyes (tearing).

Risk factors

  • Exposure to infected individuals (highly contagious).
  • Crowded environments (schools, daycare).
  • Seasonal variation (more common in colder months).
  • Stress, fatigue (may increase susceptibility).

Diagnosis

Clinical assessment

Diagnosis based on typical cluster of upper respiratory symptoms. Usually mild and self-limiting. Differentiate from influenza (more abrupt onset, high fever, myalgia, severe fatigue), allergic rhinitis (itchy nose/eyes, sneezing triggered by allergens, no fever), bacterial sinusitis (purulent discharge, facial pain/pressure, symptoms >10 days or worsening), Strep throat (sore throat predominant, fever, tonsillar exudates, tender nodes, absence of cough/rhinorrhea).

Investigations

  • Usually none required.

Diagnostic criteria

Clinical diagnosis based on characteristic symptoms.

Management

Non-pharmacological management

  • Reassurance (viral, self-limiting).
  • Rest.
  • Increased fluid intake (warm drinks may be soothing).
  • Symptomatic Relief:
  • - Saline nasal drops/spray for congestion.
  • - Nasal bulb suctioning for infants.
  • - Humidified air / Steam inhalation.
  • - Throat lozenges or gargling with salt water for sore throat.
  • - Keep child warm.
  • - Continue breastfeeding infants.

Pharmacological treatment

  • Antibiotics: NOT indicated.
  • Analgesia/Antipyretics: Paracetamol or NSAIDs for headache, sore throat, fever.
  • Decongestants:
  • - Oral (e.g., Pseudoephedrine): May provide temporary relief from congestion (use with caution - side effects like increased BP/HR, insomnia).
  • - Topical Nasal (e.g., Xylometazoline 0.05-0.1% drops/spray): Effective for congestion, but use limited to 3-5 days maximum to avoid rebound congestion (rhinitis medicamentosa).
  • Antihistamines: Generally not effective for cold symptoms unless allergic component present.
  • Cough Suppressants/Expectorants: Limited benefit, generally not recommended (especially avoid cough/cold preparations in children <6 years).

Monitoring

  • Monitor for resolution of symptoms (usually within 7-10 days).
  • Monitor for development of complications.

Complications

  • Acute Otitis Media (ear infection)
  • Acute Sinusitis
  • Lower respiratory tract involvement (bronchitis, pneumonia - uncommon)
  • Exacerbation of asthma

Prevention

  • Frequent handwashing with soap and water or alcohol-based hand rub.
  • Avoiding close contact with infected individuals.
  • Avoiding touching eyes, nose, mouth.
  • Covering coughs and sneezes.
  • Adequate rest, nutrition.

Patient education

  • Explain it's a viral cold, antibiotics won't help.
  • Focus on rest, fluids, symptom relief.
  • Explain expected duration (7-10 days).
  • Advise on hygiene measures to prevent spread.
  • Educate on signs of complications and when to return.

Uganda-specific notes

Very common. Important to distinguish from more serious conditions like malaria, pneumonia, or influenza. Avoid unnecessary antibiotic use.

References

  • Uganda Clinical Guidelines (UCG) 2023

    Chapter 5, Section 5.2.3

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