Doctors Revision

IMCI · Age: 2 months - 5 years

Severe Persistent Diarrhoea

Classification for a child whose diarrhoea has lasted 14 days or more AND who has signs of dehydration present. Requires urgent referral for specialized management.

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Care priority and warning signs

Care priority

Refer URGENTLY (after treating dehydration if severe)

Red flags

  • Signs of Severe Dehydration.
  • Signs of severe malnutrition.
  • Signs of associated sepsis or other severe infection.

Assessment

  • Ask: Does the child have diarrhoea?
  • Ask: For how long? (Response is 14 days or more).
  • Assess for Dehydration (Look/Feel for signs of Some or Severe Dehydration - see IMCI_2M5Y_005 & 006 assessments).

Classification

  • Diarrhoea for 14 days or more AND Dehydration present (Signs of Some or Severe Dehydration) -> SEVERE PERSISTENT DIARRHOEA

Key features

  • Diarrhoea duration of 14 days or more.
  • Presence of signs classifying as SOME DEHYDRATION or SEVERE DEHYDRATION.
  • High risk for malnutrition and underlying infections (including HIV).

Management

Non-pharmacological management

  • Treat dehydration first (Plan C if severe, Plan B if some) BEFORE referral, unless the child has another severe classification requiring immediate referral.
  • If referring, keep child warm.

Pharmacological treatment

  • Treat dehydration as per Plan C or Plan B.
  • If child has another severe classification (e.g., Very Severe Febrile Disease), give pre-referral treatments for that condition (e.g., antibiotic, antimalarial).

Pre-referral treatment

  • Stabilize hydration as much as possible (start Plan C or B).
  • Give other essential pre-referral treatments if needed for co-existing severe classifications.
  • Keep child warm.
  • Advise mother to continue breastfeeding.

Follow-up

  • To be managed at referral hospital, which will investigate cause and provide specialized feeding/treatment.

Counselling points

  • Explain that the long duration of diarrhoea combined with dehydration is serious and requires hospital care.
  • Explain any dehydration treatment being given.
  • Advise mother to continue breastfeeding frequently.
  • Advise on keeping child warm during transport.
  • Write a detailed referral note mentioning duration of diarrhoea, dehydration status, and any treatments given.

Differential diagnosis

  • Persistent Diarrhoea (without dehydration)
  • Acute Diarrhoea with Dehydration
  • Secondary lactose intolerance
  • Cow's milk protein allergy
  • Other food intolerances/allergies
  • Post-enteritis syndrome
  • Giardiasis
  • Cryptosporidiosis (especially if HIV+)
  • Other specific enteropathogens
  • Malnutrition-associated gut changes

Complications

  • Severe malnutrition
  • Micronutrient deficiencies
  • Severe dehydration and shock
  • Sepsis
  • Electrolyte imbalance
  • Death

Prevention

  • Appropriate management of acute diarrhoea (ORS, Zinc, continued feeding).
  • Good nutrition, Vitamin A.
  • Measles vaccination.
  • Handwashing, safe water/sanitation.
  • Early identification and management of HIV infection.

References

IMCI Chart Booklet - Page 3, Pages 13, 16

For learning and professional reference. Use current local guidance and clinical judgement.

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