Doctors Revision

IMCI · Age: 2 months - 5 years

Severe Complicated Measles

Classification for a child with measles now (or within last 3 months) who has any general danger sign OR clouding of the cornea OR deep/extensive mouth ulcers. Requires urgent referral and specific pre-referral treatments.

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Care priority and warning signs

Care priority

Refer URGENTLY

Red flags

  • Any general danger sign
  • Clouding of cornea
  • Deep or extensive mouth ulcers
  • Signs of pneumonia (chest indrawing, fast breathing)
  • Stridor
  • Severe malnutrition

Assessment

  • Ask: Does the child have fever?
  • Ask: Has the child had measles within the last 3 months? (Look for generalized rash PLUS one of: cough, runny nose, red eyes).
  • If Yes to Measles:
  • Check for General Danger Signs (Any ONE: Unable to drink/breastfeed, Vomits everything, Had convulsions, Lethargic/unconscious, Convulsing now).
  • Look: Look for clouding of the cornea.
  • Look: Look for deep or extensive mouth ulcers.

Classification

  • Measles now or within last 3 months AND (Any general danger sign OR Clouding of cornea OR Deep/extensive mouth ulcers) -> SEVERE COMPLICATED MEASLES

Key features

  • History of measles (rash + cough/runny nose/red eyes) within last 3 months.
  • Presence of ANY General Danger Sign OR Clouding of Cornea OR Deep/extensive mouth ulcers.
  • Clouding of cornea indicates severe Vitamin A deficiency and risk of blindness.
  • Deep mouth ulcers impair feeding and increase risk of secondary infection/dehydration.
  • Requires Vitamin A, pre-referral antibiotic, and urgent referral.

Management

Non-pharmacological management

  • Quickly complete assessment.
  • Keep child warm.
  • Provide supportive care for breathing/airway if needed.

Pharmacological treatment

  • Give Vitamin A treatment dose TODAY (Day 1). Dose: Age 6-11 months: 100,000 IU (Blue capsule). Age 12 months - 5 years: 200,000 IU (Red/Yellow capsule). (Note: Give 2nd dose on Day 2, 3rd dose after 2 weeks if eye signs present - managed at referral).
  • Give first dose of appropriate IM antibiotic (e.g., Ampicillin + Gentamicin or Ceftriaxone - see page 12 for doses).
  • If clouding of cornea or pus draining from eye: Apply Tetracycline eye ointment (1%) into both eyes.
  • Treat to prevent low blood sugar (as per page 12).
  • Give other necessary pre-referral treatments (e.g., rectal diazepam, antimalarial if co-existing severe classification).

Pre-referral treatment

  • Vitamin A Day 1 dose.
  • First dose IM antibiotic.
  • Tetracycline eye ointment if eye signs.
  • Treat for low blood sugar.
  • Other essential pre-referral treatments.

Follow-up

  • To be managed at referral hospital facility.

Counselling points

  • Explain that measles has caused serious complications requiring hospital care.
  • Explain treatments given (Vit A, antibiotic, eye ointment).
  • Advise on keeping child warm and continuing fluids/breastfeeding if possible during transport.
  • Write a detailed referral note mentioning measles, complications found, and all treatments given.

Differential diagnosis

  • Measles with Eye/Mouth complications (less severe)
  • Uncomplicated Measles
  • Other viral exanthems (e.g., Rubella, Dengue, Enterovirus)
  • Kawasaki disease
  • Drug reaction
  • Severe Vitamin A deficiency (corneal signs)
  • Herpetic stomatitis (mouth ulcers)

Complications

  • Blindness (from corneal ulceration/scarring)
  • Severe Pneumonia
  • Encephalitis
  • Severe Diarrhoea and Dehydration
  • Severe Stomatitis leading to poor intake/malnutrition
  • Otitis Media, Mastoiditis
  • Sepsis
  • Subacute Sclerosing Panencephalitis (SSPE - late complication)
  • Death

Prevention

  • Measles vaccination (2 doses as per national schedule).
  • Vitamin A supplementation (routine).
  • Good nutrition.
  • Prompt treatment of uncomplicated measles.
  • Isolation of cases to prevent spread.

References

IMCI Chart Booklet - Page 4, Pages 1, 12, 18 (eye ointment), 20 (Vit A)

For learning and professional reference. Use current local guidance and clinical judgement.

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