Doctors Revision

IMCI · Age: 2 months - 5 years

Severe Anaemia

Classification for a child presenting with severe palmar pallor (palms look very pale, almost white). This indicates severe anaemia requiring urgent investigation and management, likely including referral.

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Care priority and warning signs

Care priority

Refer URGENTLY

Red flags

  • Signs of heart failure (difficulty breathing, fast breathing, enlarged liver)
  • Signs of shock (lethargy, cold extremities)
  • Any general danger sign
  • Jaundice (suggests hemolysis)

Assessment

  • Look/Feel: Look at the child's palms. Are they very pale? (Severe Palmar Pallor). Compare with your own palm or another healthy person's palm if unsure.

Classification

  • Severe palmar pallor -> SEVERE ANAEMIA

Key features

  • Presence of Severe Palmar Pallor is the key sign.
  • Indicates a critically low level of haemoglobin.
  • Requires urgent assessment for cause and likely referral for transfusion/further management.

Management

Non-pharmacological management

  • Handle child gently.
  • Keep child warm.
  • Minimize exertion.

Pre-referral treatment

  • Assess for and manage any associated severe conditions requiring pre-referral treatment (e.g., give pre-referral antimalarial if also Very Severe Febrile Disease, antibiotic if severe infection, manage shock/hypoglycemia).
  • Do NOT give iron pre-referral.
  • If Sickle Cell Disease (SCD) is suspected or known, manage appropriately (hydration, pain relief - specific pre-referral protocols may apply).

Follow-up

  • To be managed at referral hospital facility (investigation of cause, blood transfusion if needed, specific treatment).

Counselling points

  • Explain that the child is very pale, which is serious and needs urgent hospital care.
  • Explain any pre-referral treatments given.
  • Advise on keeping child warm and calm during transport.
  • If SCD is suspected, explain the need for specific tests/care.
  • Write a detailed referral note indicating severe palmar pallor and any associated findings/treatments.

Differential diagnosis

  • Anaemia (non-severe)
  • Causes of severe anaemia: Severe malaria, Iron deficiency (usually chronic, severe is less common acutely), Hookworm infestation, Sickle Cell Disease crisis (vaso-occlusive or sequestration), Other haemoglobinopathies, Hemolysis (G6PD deficiency, autoimmune), Bleeding (chronic or acute), Malignancy (leukemia), Aplastic anaemia, Chronic kidney disease, Severe malnutrition.

Complications

  • Heart failure
  • Shock
  • Impaired consciousness
  • Organ damage due to hypoxia
  • Death

Prevention

  • Malaria prevention (ITNs).
  • Iron supplementation where indicated/routine.
  • Deworming.
  • Good nutrition.
  • Early diagnosis and management of Sickle Cell Disease.
  • Prompt treatment of conditions causing anaemia.

References

IMCI Chart Booklet - Page 7

For learning and professional reference. Use current local guidance and clinical judgement.

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